Angelman’s Syndrome is a genetic syndrome characterized by severe delay in psychomotor development, severely impaired or absent speech, dynamic balance deficit and uncoordinated movements (ataxia) with tremors in the limbs, typical behavior characterized by generally happy demeanor and ease in relating, motor hyperactivity, hyperexcitability with reduced attention span, rare bouts of unmotivated laughter. These characteristics are common to all affected people. Other frequent traits, present in 80% of cases, are microcephaly, which becomes evident after 2 years of life and epileptic seizures that generally arise within 3 years of life.

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